The Benefactor (novel) 1963

Against Interpretation and Other Essays (essays) 1966

Death Kit (novel) 1967

Duet for Cannibals [and director] (screenplay) 1969

Styles of Radical Will (essays) 1969

Trip to Hanoi (essay) 1969

Brother Carl: A Filmscript [and director] (screenplay) 1971

Promised Lands [and director] (screenplay) 1974

On Photography (nonfiction) 1977

I, etcetera (short stories) 1978

Illness as Metaphor (nonfiction) 1978

Under the Sign of Saturn (essays) 1980

A Susan Sontag Reader (essay collection) 1982

Unguided Tour [and director] (screenplay) 1983

“The Way We Live Now” [republished as a novella in 1991] (short story) 1986

AIDS and Its Metaphors (nonfiction) 1989

The Volcano Lover: A Romance (novel) 1992

Alice in Bed: A Play in Eight Scenes (drama) 1993

In America: A Novel (novel) 2000

Where the Stress Falls (essays) 2001

Regarding the Pain of Others (nonfiction) 2003