Act I, Scene i

Spike Heels begins in Andrew's apartment. Georgie, his neighbor, comes home from work in a bad mood. She is dressed in her work attire, including spike-heeled shoes. She changes clothes in front of Andrew, which makes him uneasy. While venting to Andrew, she reveals that her boss, Edward, has made unwanted sexual advances and threatened her with rape. Andrew becomes very upset, and Georgie unsuccessfully tries to seduce him. When Andrew reveals that he informally allowed Edward to pursue her, Georgie becomes enraged and storms out.

Act I, Scene ii

The second scene is also set in Andrew's apartment, one day later. Edward shows up unexpectedly to see his friend before taking Georgie out on a date. Andrew tells him he is not welcome. The two argue about Edward's behavior toward Georgie. Georgie arrives, dressed provocatively, and Andrew manages to get Edward to step out for a moment to talk to her. As he attempts to remove her spike heels, they share a passionate kiss, but he pulls away. Georgie and Andrew argue about their relationship, and in his anger, Andrew inadvertently reveals that he believes he "made her." Offended and furious, Georgie returns to her apartment to wait for Edward.

Act II, Scene i

The second act takes place in Georgie's apartment. Scene 1 begins later that same night. Georgie and Edward are back at her apartment, making out on the couch. She tries to seduce him, but he resists, wanting to discuss her relationship with Andrew. When she refuses, he becomes insulting, which upsets her. They are interrupted by a loud knock on the door: it's Lydia, who is very angry, suspecting Georgie of having an affair with Andrew. Edward leaves, and Lydia and Georgie talk about Lydia's relationship with Andrew, who has recently postponed their wedding. They end up dancing together but stop when there's another knock at the door—it is Edward and Andrew. Edward persuades Andrew to confess his love to Georgie, unsettling both Lydia and Georgie, leading the two women to leave.

Act II, Scene ii

As the scene begins, the two men are waking up in Georgie's apartment. They continue discussing the previous night's events, and Andrew admits that he and Lydia slept together while she was still with Edward. Georgie returns, and after she gets Edward to leave, Andrew expresses his feelings to her once more, but she rejects him. Andrew leaves, Edward comes back, and the play concludes with Georgie and Edward contemplating if they will pursue a relationship with each other.