Albee himself directed the initial production of Seascape on 26 January 1975, at the Sam S. Shubert Theatre in New York City. This work depicts an aging couple who are accosted on a beach by a pair of intelligent lizard-like creatures that have been driven from the sea by the processes of evolution. The four characters discuss topics of mutual understanding, including the purpose of existence, before concurring that human and alien creatures should aid and inspire one another to shape the conditions of life.
Albee received his second Pulitzer Prize for Seascape. Although Walter Kerr found the play "predictable" and lacking dramatic energy and Stanley Kauffmann judged it "banal," many early reviewers commended its originality and—as several critics termed it—"exquisite" dialogue. Critical commentary on Seascape has focused on its analysis of existence, death, and the human spirit. Liam O. Purdom has viewed the play as a "treatise on human psychology," and Gerry McCarthy has seen it as a consideration of "the phenomenon we know as life and experience personally as existence." Lucinda P. Gabbard has read the play's "principal concern" as "the realization of the proximity of death," an awareness that Albee has gentled by means of the fairy tale form. Samuel J. Bernstein has argued that in Seascape Albee "has cast a broad, piercing light on the human condition" and revealed that love "is our only weapon against the void." Finally, Matthew C. Roudané has contended that in this play "Albee is not writing merely about the naturalistic evolution of the human species, but about growth patterns of humankind, about combining the visceral and the intellectual into a new whole which is the consciously aware person."