Explain the contrast between Duncan's statements to Lady Macbeth and her plans for him.

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In act 1, scene 6, King Duncan arrives at Macbeth's castle and enthusiastically greets Lady Macbeth by referring to her as an "honored hostess." King Duncan proceeds to thank Lady Macbeth for entertaining him on such short notice, and she demonstrates her capacity for dissembling by acting like a gracious, hospitable hostess. Duncan then praises Macbeth's great love for him and refers to Lady Macbeth as a "Fair and noble hostess." King Duncan then takes Lady Macbeth's hand and displays his complete trust in her by allowing Lady Macbeth to lead him into Macbeth's castle.

King Duncan is completely unaware that Lady Macbeth is actually hostile, dangerous woman, who is carefully plotting his assassination. In the previous scene, Lady Macbeth commanded evil spirits to fill her with cruelty and enable her to act upon her violent thoughts, saying,

Come, you spirits
That tend on mortal thoughts, unsex me here,
And fill me from the crown to the toe top-full
Of direst cruelty. Make thick my blood . . .(1.5.30–34)

Lady Macbeth conceals her true intentions by graciously inviting King Duncan into Inverness, and he is completely unaware of her bloody plans to murder him. Duncan's positive comments about Lady Macbeth are entirely wrong, and the audience recognizes that he should be on guard at all times when he is around her. Duncan's inability to recognize Lady Macbeth's evil intentions, while the audience understands that she is a threat, is an example of dramatic irony.

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Duncan arrives at Macbeth's castle in Act I, scene vi thanking Lady Macbeth for taking the trouble to host him. He speaks of Macbeth and Lady Macbeth as hospitable, which would include providing protection to him as their guest. He mentions Macbeth's great love for him:

And his great love, sharp as his spur, hath holp him
To his home before us. Fair and noble hostess,
We are your guest tonight.
Duncan refers to Lady Macbeth as "noble" and says that because of his great love for Duncan, Macbeth has ridden home ahead to help prepare to greet him as a guest. 
In fact, Lady Macbeth plans to have her husband murder Duncan. Rather than offer hospitality and protection, she plans to kill this guest so that her husband can become king. This is an example of dramatic irony, which is when the audience knows something a character doesn't. In this case, the audience already knows from the previous scene that Lady Macbeth's plans for her king are anything but loving and hospitable. We know that Duncan is walking into a trap.

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