Explore the history of morphine usage and the issues surrounding morphine addiction from its chemical isolation from opium in 1806 to the current day.

Examine the evolution of sanatoria or hospitals dedicated to treating consumptive diseases and their approaches to managing tuberculosis before the advent of modern vaccines and chemotherapy.

Investigate the hardships faced by Irish Catholic immigrants arriving in America during the potato blight famine that hit Europe in 1845.

Choose one or more poets, novelists, or playwrights mentioned or quoted in the play and study their literary contributions and how they influenced O'Neill.

Research the condition of American theater at the close of the nineteenth century, focusing on how the profit-driven motives of commercial theaters negatively impacted production quality.