The most intense part of the story, and the reason for the title, is spiritual. Cuba, as a Communist country, is supposed to be atheistic; however, spiritual values are not changed instantly by an altering of the political climate. Most Cubans in the story are Roman Catholics; only Pilar, the most American of the family and the youngest character portrayed in detail, considers atheism as a possible way of life.

Underneath Catholicism, however, lies an even older religion. The story begins and ends with rites of Santeria, an ancient religion with roots in Africa. In its Latin American form, Santeria has taken on some of the trappings of Christianity. Most notably, ancient gods are represented by Christian saints, the legacy of attempts to cover up the practice of the ancient rituals.

Despite appearances, the ancient rites are still practiced. Animals are sacrificed, and magical herbs are used as remedies for a variety of illnesses. Even the family members in New York consult Santeria priests and priestesses when they have spiritual or physical problems. Felicia, who refused to take the rites seriously while she was alive, is buried in a Santeria funeral.