1. Are anger and hatred natural emotions? Are criminal behaviors inevitable? Can people choose different paths?

2. What advantages can scientific research offer to a scientist? To their community? To the world as a whole?

3. Is a scientist accountable for the outcomes (both positive and negative) of their research? To whom can they be held responsible? How does this influence their research?

4. What should be the focus of human study? Are there certain things that humanity was never meant to understand? The clichés in these questions are assumed to include women too—or do they? Why?

5. Compare Dr. Jekyll and Mr. Hyde with Mary Wollstonecraft Shelley's novel Frankenstein. What are the scientists attempting to discover? What flaws are exposed in the scientists? What shortcomings are found in their research materials? Above all, what is revealed by their studies?

6. In a time when the human genome is studied for both personal gain and the benefit of humanity, what lessons can be learned from Dr. Jekyll and Mr. Hyde?

7. When human behaviors are labeled as "good" or "bad," what are some of the consequences? Do behaviors have intrinsic value, or do circumstances play a role? Are there any moral absolutes?

8. What is tuberculosis? How is it spread? What treatments are currently available to prevent or cure it? How many people contracted tuberculosis last year in your home country? In the world? Why is tuberculosis still a problem today?

9. Would Stevenson have used his moderate wealth to buy health if it had been possible at the time? Was his travel solely due to his health issues?

10. How would the story change if Poole had been an assertive and confident assistant instead of a subservient servant? How might Samuel Beckett have written this story? Or perhaps your favorite author?