The last accused witch was executed in England in 1682, almost eighty years after the death of Elizabeth; however during her reign, trials and convictions for witchcraft had declined dramatically. The reason had little to do with Elizabeth, but rather was due to the influence of more modern thinking about causes and events. Supernatural explanations were no longer accepted on face value.
Witchcraft trials in Europe expanded after Pope Innocent III believed that witches had caused him to become impotent. As a result, he issued a Papal Bull which read in part:
It has indeed lately come to Our ears, not without afflicting Us with bitter sorrow, that in some parts of Northern Germany, as well as in the provinces, townships, territories, districts, and dioceses of Mainz, Cologne, Tréves, Salzburg, and Bremen, many persons of both sexes, unmindful of their own salvation and straying from the Catholic Faith, have abandoned themselves to devils, incubi and succubi, and by their incantations, spells, conjurations, and other accursed charms and crafts, enormities and horrid offences...they blasphemously renounce that Faith which is theirs by the Sacrament of Baptism, and at the instigation of the Enemy of Mankind they do not shrink from committing and perpetrating the foulest abominations and filthiest excesses to the deadly peril of their own souls, whereby they outrage the Divine Majesty and are a cause of scandal and danger to very many.
Those primarily accused were women, who were considered the source of all evil (the word derives from "Eve," who was first tempted by the Serpent) and were generally keepers of oral tradition. Large numbers were hanged or burned at the stake, generally after having confessed under torture.
Over time, the more educated began seeking natural rather than supernatural explanations for events. The fact that confessions were accepted under torture made them more suspect; and it was believed that secular courts should not meddle in religious matters. Cyrano de Bergerac once commented:
No I do not believe in witches, even though several important people do not agree with me, and I defer to no man’s authority unless it is accompanied by reason and comes from God.
Elizabeth I was much more accommodating than had been her half sister, Mary I. Executions and burnings for religious matters declined dramatically under her reign, including those for witchcraft. The decline of witchcraft trials was part of her more humane method of rule, in which she sought to compromise with all religious groups. Still, the timing for the end of witchcraft is largely coincidental to her reign.