In act 5, scene 1, the doctor and a gentlewoman watch on as Lady Macbeth sleepwalks. In her sleep, Lady Macbeth seem to relive the events of the murder which she and her husband committed earlier in the play. At one point she says, as if to her husband, "Wash your hands, put on your nightgown; look not so pale - I tell you again, Banquo's buried." These words seem to echo those she spoke to Macbeth after the murder, in act 2, scene 2, when she was, to put it mildly, annoyed with Macbeth for being so worried about the murder. In this earlier scene she told Macbeth that "A little water clears us of this deed." She also told him to "Get on (his) nightgown." In act 5, scene 1, Lady Macbeth is thus reliving her previous annoyance with Macbeth for being, as she saw it, too cowardly and too remorseful.
Lady Macbeth's words in act 5, scene 1 also seem to echo the words she has spoken to Macbeth earlier in the play. For example, she tells Macbeth after the murder that "the sleeping and the dead / Are but as pictures," and, after the appearance of Banquo's ghost, she tells an anguished Macbeth that "all's done," and that he "lack(s) the season of all natures, sleep." In these instances Lady Macbeth is again annoyed with Macbeth for being, as she sees it, too cowardly. In act 5, scene 1, she seems to be reliving these earlier moments too.