Who is the dicoverer of Alexander Disease and when was it discovered?

2 Answers

pohnpei397's profile pic

pohnpei397 | College Teacher | (Level 3) Distinguished Educator

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Alexander Disease was discovered in 1949 in Australia.  It was named for the man who discovered it, an Australian doctor by the name of Dr. W. Stewart Alexander.

The disease is a leukodystrophy -- a disease that destroys white matter in the brain.  It usually sets in during a child's infancy.  Children who have the disease rarely live past their 20s.  The disease is very rare and has only been identified in about 200 cases since its discovery.

Recently, the gene that causes the disease has been identified by Albee Messing, a researcher at the University of Wisconsin in the United States.

giorgiana1976's profile pic

giorgiana1976 | College Teacher | (Level 3) Valedictorian

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ALX, or Alexander disease, is discovered in 1949 by the Australian pathologist W. Stewart Alexander, who reported about an infantile case.

This disease is synonymous with von Willebrand disease.

Rare form of leucodystrophy in infants, characterized by macrocephaly with encephalopathy and hydrocephalus.

The aetiology is uncertain: immaturity cells would prevent nerve fibers to be wrapped up by myelin during nerve development, as usually happens. Grim prognosis, with death by the age of two years.