Put at its simplest, the main difference between prokaryotic cells and eukaryotic cells is that prokaryotes do not have a nucleus while eukaryotes do. There are, however, other differences as well. Both types of cells have a plasma membrane, DNA, and cytoplasm. All cells share these features. Even though a prokaryotic cell does not have a nucleus, it still has DNA that is contained as a complex with proteins in the cytoplasm. Golgi apparatus and lysosomes/peroxisomes, however, are only found in eukaryotic cells and not prokaryotic cells. The Golgi apparatus helps to process and distribute proteins produced by the cell and lysosomes are vesicles within the cell that perform a variety of functions including waste disposal and breakng down larger molecules.