Which characters in William Shakespeare's Macbeth flee Scotland at any point in time and fear for their own lives?

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In act 2, scene 3, Macduff and several Scottish lords arrive at Macbeth's castle and discover that King Duncan has been assassinated. After Macduff exits Duncan's chamber, he breaks the terrible news that King Duncan has been murdered, and Macbeth and his wife act like they are devastated. Duncan's...

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In act 2, scene 3, Macduff and several Scottish lords arrive at Macbeth's castle and discover that King Duncan has been assassinated. After Macduff exits Duncan's chamber, he breaks the terrible news that King Duncan has been murdered, and Macbeth and his wife act like they are devastated. Duncan's sons then enter the scene and learn about their father's assassination. Malcolm then whispers to his brother, Donalbain, that they must flee Scotland immediately because they are in danger. After the Scottish lords leave the scene, Malcolm tells his brother that he will be fleeing to England and Donalbain says that he will travel to Ireland. Macduff and Ross also choose to flee Scotland and pledge their allegiance to Malcolm in England. Unfortunately, Macduff's entire family is murdered while he is out of the country. Towards the end of the play, Malcolm leads his army against Macbeth and ends up defeating the tyrant.

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There are two characters who flee Scotland first in William Shakespeare's Macbeth. Both Malcolm and Donalbain, state that they will leave Scotland after finding out about their father's death. No that the life of their father (King Duncan) has been taken, both fear for their own lives. Malcolm states that he will go to England; Donalbain will go to Ireland. 

Later, Macduff is in England with Malcolm. Unbeknownst to Macduff, Macbeth has sent murderers to kill him and his family. Luckily for Macduff, he is in England; unfortunately for his family, they are still in Scotland (Fife to be exact) and are killed. Even later still, Ross comes to England to meet up with Malcolm and Macduff (to help with the war against Macbeth). 

While it is never stated that Macduff and Ross flee Scotland for their lives (it is only stated that Malcolm and Donalbain do), all four men do leave Scotland in order to raise a faction against Macbeth. 

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