Abraham Lincoln was assassinated by John Wilkes Booth on April 14, 1865 at Ford's Theatre. Lincoln and his wife- Mary Todd Lincoln was attending a play at the theatre. He was the first American President to ever be assassinated.
Booth snuck up to President Lincoln's private booth in the balcony during the play and shot Lincoln in the head with a 0.44 caliber Derringer. The play was already taking place. Lincoln had only one guard there with him that night; Major Henry Rathborn, and despite his best efforts to subdue the him, Booth was able to escape. He jumped from the balcony to the stage and ran off. Federal agents searched for Booth for 12 days and he was finally captured and killed in Virginia.
After being shot, President Lincoln was taken to the Petersen House, located across the street. He slipped into a coma and never regained consciousness. He was pronounced dead nine hours later.