The main function of Pancrease are

Secrete juice which help in breaking down of proteins, carbohydrate and lipids.

Secretes hormones

Secretes juice that neutralises the stomach acid that passes into the small intestine.

The Islets of Langerhans cell of pancreas secrete Glucagon, Insulin, Somatostatin which got the specific function.

So removing the pancrease will lead in the deficiency of all the above functions which will lead to death of the individual.

If the stomach acid is not neutralised by pancrease then that leads to inflamation in small intestine.

If there is no insulin in the body which function to reduce blood glucose there it will lead to diabetes, then artificial insulin has to be provided of the individual may die.

Since Pancreas has both endocrine and exocrine function removal of pancreas will lead to Hormonal imbalance.