The Indian Removal Act and its major consequence, the Trail of Tears, resulted in the further genocide and forced displacement of indigenous peoples living in their homelands southeast of the Mississippi, as well as the further colonization of indigenous people and land west of the Mississippi River. In 1830, the colonial settler and slaveowner president Andrew Jackson enacted the Indian Removal Act, which catalyzed the death, enslavement, imprisonment, and displacement of tens of thousands of indigenous peoples.
In particular, the Indian Removal Act sought to forcibly displace the Cherokee, Choctaw, Chickasaw, Muscogee Creek, and Seminole tribes from their homelands and force them to relocate west of the Mississippi River. Through the Indian Removal Act, the tribes were given a horrific ultimatum: they were told that they had to be either forcibly removed from their homelands or subjected to US laws that would strip away their rights and sovereignty while they remained on their lands.
The Indian Removal Act catalyzed the creation of "reservations," where tribes were forced to live (often on the least farmable tracts of land), and the creation of boarding schools, where indigenous children were stolen and forced to live and assimilate into whiteness. At these boarding schools, indigenous children were stripped of their cultures, stolen from their families, shamed and forbidden from speaking their native languages, and often physically, mentally, and sexually abused.
The cultural and physical genocidal effects of the Indian Removal Act, committed by the United States, are felt today through the continuation of colonization of indigenous land; the abuse, oppression, imprisonment, and murder of indigenous people; the refusal to give back stolen land; and the very existence of the US government on this stolen land.