I agree mostly with the answer above, except for the geographic breakdown of who lived where. The geographic split between federalists and anti-federalists tended to be living followed a much more east-west line than north-south one. Federalists were much more likely to be coastal and urban, while anti-federalists were much more likely to be from the interior, rural regions.
A rich merchant from New York or Charleston, then, was more likely to support the Federalists. A yeoman farmer from Appalachia or western Pennsylvania was more likely to support anti-federalists. Massachusetts was cut in half by these sentiments, with Boston and the Cape heavily Federalist, and all of the western farm country on the anti-federalist side.
Federalists also tended to be wealthier and better educated, more organized and had control over most of the newspapers of the time.
Well known Federalists included George Washington, Ben Franklin, John Adams and Alexander Hamilton.
Famous anti-federalists included Thomas Jefferson, James Madison, Thomas Paine, James Madison and Patrick Henry.
In general (but only in general) the Federalists were from the Northeast and were typically richer and more involved in manufacturing and trade and such. The Antifederalists were more from the South and were typically more involved in agriculture.
The Federalists wanted a strong national government. They did not trust the people as much as the Antifederalists did. They thought the national government would be more insulated from public opinion and would therefore do a better job than the state governments. They worried that state governments would let the poor tyrannize the rich.
The Antifederalists believed more in democracy and thought that the state governments would be more democratic. They worried that the national government would tyrannize them.
the Federalist wanted the constitution and the antifederalist did not