In human history, commercial exchange tends to promote other changes because the people who engage in the commercial exchange also engage (whether purposefully or not) in other sorts of exchanges.
Perhaps the most important change that was fostered by commercial exchange on the Silk Road was religious. It was along the Silk Road that Buddhism made its way from India to China. Buddhism became a very important religion in China. Chinese monks ended up moving back and forth on the Silk Road to India to study and collect texts.
In this and other ways, the trade that was conducted along the Silk Road caused cultural change to occur.