What are the specific steps of the Krebbs Cycle, and what does it produce?

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orchid101's profile pic

orchid101 | College Teacher | (Level 1) Associate Educator

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Aerobic oxidation of pyruvic acid through a series of reactions was studied in detail by Hans Krebs(1943) and hence, the pathway was termed as Krebs cycle. The Krebs cycle is also known as tricarboxylic acid cycle or citric acid cycle. Once the pyruvic acid is produced by glycolytic breakdown of glucose in the cytosol, it enters into the mitochondrial matrix, where it is converted to a 2 carbon acetyl Co-A by decarboxylation reaction.

Following steps involved:

pyruvic acid------Acetyl Co-A

Iso-citric acid-----Oxalo succinic acid

Alpha-Ketoglutaric acid-------succinyl Co-A

Succinyl Co-A--------succinic ACID

Succinic acid-----------fumaric acid

Malic acid------------oxaloacetic acid

senioreeto's profile pic

senioreeto | Student, Undergraduate | (Level 1) Valedictorian

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KREBS CYCLE:krebs cycle,also known as the citric acid cycle,is the stage of aerobic respiration in which citric acid,carbon dioxide and some amino acids are produced from pyruvic acid with the help of some enzyme-controlled reactions.this process takes place in the mitochondrion of the cell.energy is released in this process in the form of ATP,GTP,NADH and FADH2.

STEPS INVOLVED:the various steps involved in this process are:

pyrivic acid+coenzyme A--->acetyl-CoA+NADH+CO2.

acetyl-CoA+oxaloacetate--->ctric acid.

citric acid+energy--->alpha-ketoglutaric acid+NADH+CO2.

alpha-ketoglutaric acid+coenzyme A--->succinyl-CoA+NADH+CO2.

succinyl-CoA+energy--->succinate+ATP+GTP.

succinate+energy--->fumarate+FADH2.

fumarate+H2O--->malic acid.

malic acid+energy--->oxaloacetate+NADH.

this oxaloacetate then again enters in the cycle to continue the process from step#2 onwards.

monoman's profile pic

monoman | Student, Undergraduate | (Level 1) eNoter

Posted on

KREBS CYCLE:krebs cycle,also known as the citric acid cycle,is the stage of aerobic respiration in which citric acid,carbon dioxide and some amino acids are produced from pyruvic acid with the help of some enzyme-controlled reactions.this process takes place in the mitochondrion of the cell.energy is released in this process in the form of ATP,GTP,NADH and FADH2.

STEPS INVOLVED:the various steps involved in this process are:

pyrivic acid+coenzyme A--->acetyl-CoA+NADH+CO2.

acetyl-CoA+oxaloacetate--->ctric acid.

citric acid+energy--->alpha-ketoglutaric acid+NADH+CO2.

alpha-ketoglutaric acid+coenzyme A--->succinyl-CoA+NADH+CO2.

succinyl-CoA+energy--->succinate+ATP+GTP.

succinate+energy--->fumarate+FADH2.

fumarate+H2O--->malic acid.

malic acid+energy--->oxaloacetate+NADH.

this oxaloacetate then again enters in the cycle to continue the process from step#2 onwards.(by MONOMAN)

 

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