There are several quotes that show both that relationships are tightly regulated by Big Brother and that any pleasure in relationships is discouraged. Further, O'Brien admits to Winston that eventually the party will sever what relationships remain completely so that the only loyalty left is loyalty to the Party.
O'Brien says to Winston:
We have cut the links between child and parent, and between man and man, and between man and woman. No one dares trust a wife or a child or a friend any longer. But in the future there will be no wives and no friends. Procreation will be an annual formality like the renewal of a ration card. We shall abolish the orgasm. Our neurologists are at work upon it now. There will be no loyalty, except loyalty towards the Party. There will be no love, except the love of Big Brother. (336-337)
He's explaining that the Party has already removed many of the relationships people used to value. But the desires for connection and pleasure that remain threaten the Party...
(The entire section contains 643 words.)