The two bodies could not be more dissimilar. Senators are elected for six years, Representatives for two; the minimum age for Senators (30) is five years older than that for Representatives (25). The Senate is much more open to debate than the House. Filibusters, attempts to kill bills by talking continuously, only occur on the floor of the Senate. Riders or amendments to bills in the Senate may take any form and need not be germane to the original bill. All debate on the floor of the Senate is done after reports from committees.
The House requires that all riders to bills be germane to the bill under debate. The House frequently adjourns and reconvenes as the Committee of the Whole House for the State of the Union. When so sitting, the Speaker normally steps down from his seat, and can engage in debate on the floor. The committee rises and reconvenes only for purposes of voting, not debate. When votes are taken, the Speaker has a vote as does every other member.
The President of the Senate is the Vice President of the United States; however he is not a member of the Senate and may note debate. He may only vote in the event of a tie.