Brave New World takes places largely in London, England and the outlying areas. The year is 2495, by our understanding of the calendar. For them, it is A.F. 632 (After-Ford). By Ford, Huxley does mean Henry Ford, the inventor of the Model T and the assembly line. All of this is symbolic, as Ford's concepts of industry are the foundations upon which this society is built--so much so that they worship Ford as a god. A great deal of the action takes place in or around the Central London Hatchery and Conditioning Centre (the place where all of the embryos are made).
There is also a "savage" reservation in New Mexico that is visited by the New Worlders looking to take a vacation. It's almost comparable to going on safari and taking in the sights and wild creatures. The people on the reservation will remind you of Native Americans in their look and customs. There's a great twist when our protagonist and his companion go on holiday to the savage reservation, though. Be on the lookout for that!
I've included some of eNotes' resources on the setting and other key points that are useful to you before or as you get started on the novel.
Hope this helps you some!