What Renaissance landmarks or personalities have influenced most dramatically the culture of the West? How so?

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There are many iconic landmarks, cultural icons, and important figures that have influenced the subsequent development of Western culture. Some of the most important are as follows.

Copernicus and Galileo: These two thinkers advanced the heliocentric model of the solar system, one that is now universally accepted. They were pioneers of the scientific method and radically changed the way people viewed the nature of the universe and humanity's place...

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