What relevance do antigen-antibody reactions have in blood transfusion?  

Expert Answers

An illustration of the letter 'A' in a speech bubbles

Before someone receives a blood transfusion we need to take a sample of their blood and perform typing, screening, and a crossmatch. This tells us among other things what the blood type is. 

If the person has for example type A blood, this means that A antigens or proteins are present. If the person receives a blood transfusion with incompatible blood they will experience a blood transfusion reaction. This occurs because the body produces antibodies to the foreign blood.

When antibodies are produced to a type of blood agglutination or clumping occurs. This is a serious event because the intravascular blood will clot. This damages organs to the point of organ failure.

Approved by eNotes Editorial Team

We’ll help your grades soar

Start your 48-hour free trial and unlock all the summaries, Q&A, and analyses you need to get better grades now.

  • 30,000+ book summaries
  • 20% study tools discount
  • Ad-free content
  • PDF downloads
  • 300,000+ answers
  • 5-star customer support
Start your 48-Hour Free Trial