At the beginning of Act V, Lady Macbeth is caught sleepwalking and sleep-talking by the doctor and her woman in waiting. These two people in Lady Macbeth's life know her well and know that these behaviors are not a part of her normal performance at night. Plus, the things that she yells as she is sleepwalking are very disturbing and curious to those who are sane. Lady Macbeth is heard to say, "Out, damn'd spot! out, I say!" (V.i.33) as she refers to an imaginary spot of blood that she finds on her hand. This odd behavior worries those who watch her, an in effect, hopefully, the audience becomes worried as well.