Opium can affect the areas of the brain responsible for mood, balance and motivation. Opium binds to opiod receptors in the brain. Opiod receptors regulate emotions and internal homeostasis. People who are addicted to opium often experience severe mood swings including bouts of depression and anxiety. Opium addicts usually loose internal motivation and may stop participating in daily professional and hygienic activities. Opium does not have a strong effect on the brain’s interaction with other organs such as the stomach or heart. Most of its negative effects are limited to the cerebral cortex and central nervous system.