Mustapha Mond: Mustapha, or the variant spelling Mustafa, is an Arabic name meaning 'the chosen one.' This is a fitting name for this character because he has been chosen to be a World Controller. Mond in Dutch means mouth, making this a fitting surname, too. Mustaph Mond is, after all, characterised in large part by his "deep, resonant voice," and he is a talker who spends much of his time lecturing and preaching.
Lenina Crowne: Crowne implies a monarch's crown, which is appropriate for this character because she is, like a monarch and by virtue of her caste, at the top of the hierarchy. Her first name, however, is somewhat ironic. Lenina means 'like a lion.' Lions are known as proud, strong, and courageous animals. Lenina shares none of these attributes. She is instead vapid and conforming.
Helmholtz Watson: This character takes his name from two people from the real world, both of whom were well-known when Huxley was writing Brave New World. Hermann Helmholtz (1821–1894) was a prominent German physicist who was best known for his work on, and theories about, vision. John B. Watson (1878–1958) was an American psychologist who founded the school of thought known as behaviorism. The character Helmholtz Watson sees differently from most people in Brave New World, linking him to his first namesake. He enjoys art and he tries to escape his conditioning to see the world in a more emotional way. As a lecturer at the College of Emotional Engineering, Helmholtz Watson is also, like the second of his namesakes, concerned about the psychology of his fellow man.