What is an important quote in act 5? Explain its significance, what it has to do with plot progressions, character foreshadowing and development, thematic concerns etc.

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As Iago has built up Rodrigo to be willing to kill Cassio in order to gain favor with Desdemona, he is almost ready to give up the fight but Iago convinces him once more to give it a go.  As he goes forth to strike Cassio, Iago says:

I have rubb'd this young quat almost to the sense,
And he grows angry. Now, whether he kill Cassio,
Or Cassio him, or each do kill the other,
Every way makes my gain.

The reference to a vegetable or fruit is notable as Shakespeare often uses the imagery of the garden for various purposes.  It shows us Iago's incredible ego as he believe that no matter what his plan will succeed.  Of course, in the next few lines he realizes that no, in fact Cassio must die for him to succeed but no matter, he will find a way to accomplish his purpose, that he never doubts.

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