Part of the irony of this story is that Granny feels she is on her feet now "morally speaking".  However, she is dying isolated, waiting for a sign from God that never comes.  She pleads, "God, give a sign!"  However, "For a second time there was no sign. Again no bridegroom and the priest in the house."  At her death her mind flashes back to the day she was jilted by George.   She feels the grief as she did that day, "She could not remember any other sorrow because this grief wiped them all away."  Even though she kept her life and house in order she never experienced true spirituality because of the guilt she felt and her inability to forgive George. "Oh, no, there’s nothing more cruel than this – I’ll never forgive it."  Granny took her guilt and her secret with her to the grave.

The dramatic irony in The Jilting of Granny Weatherall is that the main character does not fully understand the connection between her death and her jilting.

The final irony for Granny Weatherall is that in death she is finally free of the haunting memory of the day she was jilted. The sorrow of her final jilting is so great that "she could not remember any other because this grief wiped them all away."