The First Amendment is first for a reason. It is in many ways the most important and significant of the amendments. It is the First Amendment that protects our most important political rights and it is the First Amendment that protects our freedom of conscience.
Of all the amendments in the Bill of Rights, the First Amendment is the only one that truly protects political rights. It protects all the rights that allow us to speak out against the government. By protecting our speech and our press and our right to assemble and to petition, it allows us to say whatever we want (and in whatever way we want) about the government. This right is the foundation of a democracy.
In addition, the First Amendment preserves our religious rights. By doing so, it protects our right to listen to the dictates of our own consciences. This is one of the most important personal rights we can have.
In these ways, the First Amendment is important and significant because it protects our most important political and personal rights.