What impact did Uncle Tom's Cabin by Harriet Beecher Stowe have on American history?

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"So you're the little lady who started this great big war," Abraham Lincoln is reported to have said upon meeting Harriet Beecher Stowe , referring to her 1852 novel, and the role it had played in the beginning of the War Between the States in 1861.  Stowe wrote the novel, which was a vicious attack on the institution of slavery, slaveowners, and their overseers, as a reaction to/protest of the 1850 Fugitive Slave Act, which...

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