Jesus throws everything off balance by causing the Misfit to question his murderous lifestyle and even, perhaps, to feel twinges of conscience over his chosen path.
The Grandmother and the Misfit have a relatively long conversation about Jesus. The Grandmother, in terror that she is going to be killed, starts crying out "Jesus, Jesus," meaning to say 'Jesus will help you' to the Misfit. She realizes, however, it is coming out sounding like a curse.
The Misfit responds to the Grandmother's words "Jesus, Jesus," by saying that Jesus threw everything off balance. He goes on a little later to add to this idea:
Jesus was the only One that ever raised the dead," The Misfit continued, "and He shouldn't have done it. He shown everything off balance. If He did what He said, then it's nothing for you to do but throw away everything and follow Him, and if He didn't, then it's nothing for you to do but enjoy the few minutes you got left the best way you can by killing somebody or burning down his...
(The entire section contains 2 answers and 579 words.)