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This quote comes from Act IV scene 3, and is part of a rather heated conversation that Brutus has with Cassius, where he accuses Cassius of not supporting him because he did not send money to Brutus so he could pay for more legions to support him. This scene is very important therefore as representing a major split in their friendship and in the leadership of the rebel side led by Brutus.
Therefore, Cassius is actually saying to Brutus through these words that by accusing him of such deeds, he is denying their friendship and not recognising the many ways in which Cassius has been a friend to Brutus throughout the play. It is accusations such as these from Brutus that lead him to threaten to commit suicide to prove his loyalty to Brutus.
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