Candy recognizes from the earliest of moments that Curley's wife represents more challenge than anything else. His warning to George and Lennie and the rather pointed "glove fulla vaseline" conveys how he perceives her. While he does hold a very distinctly negative view of Curley's wife, it is clear that Candy is in no position to challenge her authority. In the scene that ends chapter 5, in which Candy feebly tries to impugn her credibility, it becomes clear that Candy recognizes his own powerless in front of her. While he dislikes her, Candy also knows that he lacks the power and credibility to challenge her. The best description of Candy's feelings towards Curley's wife is seen when he discovers her lifeless body:
“You God damn tramp”, he said viciously. “You done it, di’n’t you? I s’pose you’re glad. Ever’body knowed you’d mess things up. You wasn’t no good. You ain’t no good now, you lousy tart."
Curley's condemnation of Curley's wife who is dead reveals how the low opinion that he has of her. Yet, it also reveals how powerless he is. It is here in which Candy's thoughts about Curley's wife is clear. Candy has disdain for her, but recognizes that she holds more power than he could ever have. For Candy, he has a low opinion of her, but must concede that she has the power that he will never have.
Candy thinks Curleys wife is trouble. She is the farm girl who wants to get attention from the guys by being very flirtacious even though she is married. It is dangerous because Curley, the ranch owner finds out, he will do very bad things to you because it is noted that Curley's temper is very short.