Act 1, scene 5 opens with Lady Macbeth reading a letter sent to her by her husband, detailing his encounter with the witches. Considering just how potentially incriminating this information might be (even without the assassination, one can easily imagine that news of this encounter with the witches would hurt his standing with the Crown), this suggests that Macbeth places a great deal of trust in Lady Macbeth. As the scene continues, one gets the sense that the two are political partners and collaborators in addition to husband and wife.
At the same time, it's interesting to note how Lady Macbeth defies the traditional expectations of femininity, even denouncing those qualities as she perceives them in herself. She is ruthlessly ambitious, to such a degree that she criticizes her husband as being held back by his kindness, and she takes the initiative, telling Macbeth to leave the plotting of Duncan's murder to herself. In this, she also reveals her deceitfulness, instructing Macbeth,
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