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Pontiac's Rebellion was a response to the aftermath of the French and Indian War. For some time, Native peoples who lived from the Ohio Valley to the Great Lakes region had long allied (or at least leaned toward) the French, who cultivated extensive trade and diplomatic connections with them. The French and Indian War had begun as a struggle for control of the Ohio Valley, and most Indian peoples in that region, including the Shawnee, the Miami, and others, supported the French in that struggle. The British (and also, very significantly, their Iroquois and of course colonial allies) sought control of the region, and won it in the French and Indian War. After their victory, the British, especially General Jeffrey Amherst, treated the Ohio Valley Indians with contempt, refusing to honor traditions of reciprocity and gift-giving in trade. The relationship deteriorated, and a broad confederation of tribes, formed at a council near modern Detroit, rose against the British. Pontiac's Rebellion essentially sparked a protracted conflict in the Ohio Valley, especially on the Pennsylvania frontier, that would persist for years. The important point in direct response to the question is that Pontiac's Rebellion was a direct result of the war, or, as some historians have argued, an extension of the war.
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