What changes in medical belief and practice took place during the fifteenth century?

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During this time period, Flemish physician Andreas Vesalius published a comprehensive book about the structures and functions of the human body, as well as conducted specific research into the anatomy of the human brain.  His greatest contribution, however, may have been in correcting or disproving nearly two hundred theories and mistakes dating back to the days of the ancient Greek physician Galen.  Although this time period yielded no real advances in the field of drug therapy and pharmacology, there was a general increase by other physicians and scientists in the area of experimental research, particularly that conducted through the use of human body dissection.