The central conflict of the novel is no less than the future of humanity. This conflict plays out between a re-empowered Dracula's desire to take over the world and the desire of a small group of people who know about him to thwart his attempt.
Harker meets Dracula, an "undead" creature who can pass as a human being, in his medieval castle in the remote Carpathian mountains. Harker becomes increasingly chilled and uneasy with his host, who only appears at night, never eats, and never looks in a mirror. Harker escapes Dracula and returns to London only to find that Dracula too has arrived in London, along with other vampires followers, with the object of world domination.
London is the logical place for Dracula to start if he wants to fan out with his vampire followers and infect the world, creating a vast army of vampires. It is the capital of the most powerful nation on earth. London is also a central commercial power, with ships coming and going from its harbor at all times.
Harker and his small band must fight and block Dracula in his attempt for world domination, making for a gripping story.