Circe's early life is defined by a continual abandonment and rejection by her family. Born a girl, and without the radiant beauty of the other nymphs and goddesses, Circe is seen as having little value to contribute to the family and is frequently overlooked, ridiculed, or tormented by her parents, siblings, and relatives. Rejected by the world of the gods, Circe naturally turns to the mortal world for acceptance and love. Her investment in the mortal world is what separates her from her family and allows her to define herself outside of their values. When exiled to Aiaia, she reflects on her experience:
You threw me to the crows, but it turns out I prefer them to you.
In being rejected by her family, she is able to build an identity for herself in the mortal world that is removed from their definitions of her. Their rejection frees her in the end.
However, even though she is separated from her family, they still affect her future and actions. Her magical ability is unique to her bloodline, as only herself and her siblings, the children of Helios and Perse, are able to practice the powerful magic pharmaka. Her brother Aeetes discovers his siblings' unique talent and introduces Circe to the idea, and though her siblings are allowed to practice it to a certain extent without detection, Circe's first experimentation with pharmaka results in her banishment. She spends her exile honing this talent, one that allows her to transform, protect, and heal, and it is this ability that turns Circe into the legendary Witch of Aiaia, none of which could have been possible without the ability inherited from her family or Aeetes's curiosity.