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Sectionalism, states rights and slavery led to which event in American history?  

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The answer to this question is "secession and the Civil War." Southern secession was the result of a longstanding struggle over the issue of slavery, and especially the issue of slavery's expansion into the western territories. Long simmering, this issue first became truly divisive with the Missouri crisis over the admission of that state as a slave state in 1820. Resolved, like other crises involving slavery, by a political compromise, the crisis in many ways set the stage for future showdowns over the issue. The addition of the modern American Southwest through the Mexican War led to a new crisis, this time...

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