Out of all Shakespeare's female characters, Lady Macbeth's stands out in ambition and perseverance. Comment.
First, I believe that this question should be moved to the discussion section. I know that your will receive many more relevant answers than only one there.
Outside of that, I do not believe that Lady Macbeth (from Macbeth) is Shakespeare's most ambitious female character. That being said, she does not possess true perseverance given the fact that Lady Macbeth fails to make it through the play alive.
Lady Macbeth fails to stay true to the course once her morals begin to catch up with her. She does not push Macbeth into telling her about the plan for Banquo.
I would have to say that I believe Portia (from Shakespeare's The Merchant of Venice) is the most ambitious female character (and she makes it through the play's action alive). She, unlike many of Shakespeare's female characters does not divert from the path which she chooses.