Osteoporosis (thinning of Bone) is caused due to?
1. Parathyroid gland 2. Adrenal cortex
i m confused. because, in our book, they write,, it is caused in old women due to defeciency of ESTROGEN .. now cortex can aslo secrete some sex hormone,, it means, Adrenal cortex also hav a role in Osteo.porosis,,
now plz tell me, where i m wrong?
Osteoporosis is a debilitating disease most commonly seen in post menopausal Caucasian women. The etiology of this disease is multifactorial. When a woman experiences menopause there is a drastic reduction of several hormones, namely estrogen. Bone health and strength rely on estrogens because they play a role in osteoblast and osteoclast activity. Estrogen is secreted from the adenohypophysis (anterior pituitary gland) in both women and men. Calcium, phosphorus, and Vitamin D also play large roles in bone health, growth, and strength. Physical activity also plays a role. Chronic inactivity leads to a loss of bone matrix which leads to a weakening of the bones.
Osteoporosis, bone condition characterized by a decrease in density, resulting in bones that are more porous and more easily fractured than normal bones. Fractures of the wrist, spine, and hip are most common; however, all bones can be affected. Osteoporosis primarily affects women, who account for nearly 80 percent of all cases. White and Asian women are the most susceptible, but women of other races are also at considerable risk. Other risk factors include low calcium intake, a thin build, inadequate physical activity, certain drugs, such as corticosteroids , cigarette smoking, alcohol, and a family history of the disease.