The list of autoimmune diseases includes lupus systemic lupus erythematosus, abbreviated as SLE. As all autoimmune diseases, lupus disease confuses the immune system, making it to attack the healthy tissues, causing swelling and pain and damaging the normal tissue.
The exactly cause of lupus is not determined, but genetics and environment were often associated with lupus disease. Since there are not discovered genes that lead to this illness, it is believed that the inheritance of predisposition to lupus, associated with environmental factors, can lead to the activation of disease. For example, since women are more prone to lupus, it is believed that certain hormones can be considered triggers for lupus activation, especially estrogen hormone is suspected to have a major influence, because the lupus' symptoms are worsening during pregnancy or before menstrual periods.
But, of course, there exists some other factors that can activate the lupus, such that: antibiotics from penicillin groups, exposure to trichloroethylene, hepatitis C infections, cytomegalovirus, parvovirus, sunlight's ultraviolets exposure.
The lupus disease is classified in several categories, such that: cutaneous, neonatal and drug-induced. SLE lupus is the worst form of cutaneous lupus since it not only affects the skin, but lungs, kidneys, blood or heart. The SLE disease can be active within some periods of time and inactive in others. The neonatal lupus is a rare clinical condition and it occurs when auto-antibodies are transferred from mother to the fetus. The drug-induced lupus is activated by medication prescribed to hypertension and heart arrhythmia, called hydralazine and procainamide.
Lupus disease can cause complications in several regions of the body, such that: kidneys, lungs, heart, bone tissue, blood and vessels. Lupus can also affect the pregnancy period, leading to miscarriage and it also can increase the risk of lung cancer, liver cancer and non-Hodgkin's lymphoma.