In Of Mice and Men, how do the characters' respective dreams come to an end?

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Most of the characters share a dream to have land.  As they get to know each other, they realize that they all have this same dream.  George and Lennie have been traveling together, and they wanted to buy a ranch and raise rabbits.  This was a dream that George used to keep Lennie motivated.

"Well, it's ten acres," said George. "Got a little win'mill. Got a little shack on it, an' a chicken run. Got a kitchen, orchard, cherries, apples, peaches, 'cots, nuts, got a few berries. They's a place for alfalfa and plenty water to flood it. They's a pig pen-"

"An' rabbits, George." (Ch. 1)

George and Lennie’s dream soon extends to Candy, who also wants to buy himself some land.  He has some money saved up.  He wants to join George and Lennie in their dream, so the three of them can be together and no longer lonely.  When Crooks, the African-American stable hand, finds out about this, he is at suspicious until he realizes Candy has money.  Then he is interested too.

Unfortunately, the dreams of all of them are crushed when Curley’s wife is killed.  George has to shoot Lennie.  There will be no ranch for Lennie and George.  Theoretically, the others could get a ranch together, but it is unlikely.  The deaths of Curley’s wife and Lennie reminded them of how tenuous dreams are.

Curley’s wife had dreams too.  She once wanted to be a movie star.

"'Nother time I met a guy, an' he was in pitchers. Went out to the Riverside Dance Palace with him. He says he was gonna put me in the movies. Says I was a natural. Soon's he got back to Hollywood he was gonna write to me about it." (Ch. 5) 

He never wrote to her.  She never became a star.  She married Curley, and then he brought her to the ranch.  She was lonely there, and before she knew it, there was no one for her to talk to but Lennie.