It is clear that as the story develops and Gregor becomes more and more used to his condition as a bug, his feelings of love and compassion towards his family fade and he becomes more and more selfish and focused on his own concerns and his internal world. Note for example what Gregor does when he sees his sister arguing with their parents about the deep cleansing that their mother has just carried out of Gregor's room:
...Gregor hissed loudly in his fury because no one thought of closing his door to shield him from this spectacle and commotion.
Gregor then appears to become more and more selfish as the story progresses. At the beginning of the story, it is clear he cares very deeply for his sister and his parents, and indeed lives his whole life trying to provide for them. At this point in the novel, it is clear that this selflessness has been replaced by a certain amount of selfishness that dominates his character.