In "The Metamorphosis" how do Gregor's feelings towards his family change over the course of the story? 

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Early on, right after Gregor's transformation, he is most concerned about failing his family. The narrator says that he "hadn't the slightest intention of letting the family down." He feels that his real worth lies in his ability to work and support them, and he does not want to fail to provide. Later, in part 2, Gregor feels quite "proud that he had been able to provide . . . so nice an apartment for his parents and his sister." He certainly fears, now, that he will not be able to continue to keep them in the manner to which they have become accustomed. Gregor also has no wish to put his family out, to inconvenience them more than he already feels he is, and he will not even try to communicate to his sister that he doesn't like the food she brought him. In fact, "he would rather starve than call it to her attention." He attempts to be incredibly considerate of her and their mother's feelings.

But, by part 3, Gregor's feelings have changed.

At . . . times he was in no mood to worry about his family, he was completely filled with rage at his miserable treatment

Now, he feels resentful and even angry at the way they seem to ignore him and go about their own lives and, now, their own jobs. At one point, he even "hisses loudly with rage" at them. At this point, though, "It hardly surprised him that lately he was showing so little consideration for the others; once such consideration had been his greatest pride."

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It is clear that as the story develops and Gregor becomes more and more used to his condition as a bug, his feelings of love and compassion towards his family fade and he becomes more and more selfish and focused on his own concerns and his internal world. Note for example what Gregor does when he sees his sister arguing with their parents about the deep cleansing that their mother has just carried out of Gregor's room:

...Gregor hissed loudly in his fury because no one thought of closing his door to shield him from this spectacle and commotion.

Gregor then appears to become more and more selfish as the story progresses. At the beginning of the story, it is clear he cares very deeply for his sister and his parents, and indeed lives his whole life trying to provide for them. At this point in the novel, it is clear that this selflessness has been replaced by a certain amount of selfishness that dominates his character.

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