Yes, Chris McCandless found enormous meaning and satisfaction by living life unconventionally and following a less comfortable path than the average person. He rejected going immediately to law school, as his parents would have liked, and gave the money he had inherited—that his parents hoped would finance law school—to Oxfam. He even burned his cash.
He wanted to make his own way in the world and face reality in the manner of Thoreau or Tolstoy: through living a life stripped of most material possessions. Instead of a cushy time in law school, he worked hard at minimum-wage jobs, such as at McDonald's or working on a farm. He often moved around, hitchhiking from place to place.
Krakauer quotes James Joyce in describing McCandless as joyful and fulfilled with his life on the road:
He was unheeded, happy, and near to the wild heart of life
McCandless himself, even when he knew he was near death, attested to his own sense of gratitude and fulfillment, writing:
I HAVE HAD A HAPPY LIFE AND THANK THE LORD. GOODBYE AND MAY GOD BLESS ALL!