Expert Answers
hi1954 eNotes educator| Certified Educator

Lithium affects the flow of sodium through the nerves and muscle cells of the body, and interferes with the production and uptake of neurotransmitters in the nerves.  Because sodium increases excitation, lithium is used to treat the manic phase of Bipolar Disorder, which used to be called Manic-Depressive Syndrome.  Because it also affects the concentration of serotonin and tryptophan in the brain, it is used for treatment of other depressive disorders.  Lithium carbonate is most commonly used, but lithium saulfate, lithium citrate and other forms of lithium salts are also used.

isabellajone | Student

<!-- /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-parent:""; margin:0in; margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman"; mso-fareast-font-family:"Times New Roman";} @page Section1 {size:8.5in 11.0in; margin:1.0in 1.25in 1.0in 1.25in; mso-header-margin:.5in; mso-footer-margin:.5in; mso-paper-source:0;} div.Section1 {page:Section1;} -->

Lithium is an antipsychotic, antimanic medication used for those with Affective Disorder, Bipolar; Bipolar Disorder; Depression; Mania. Preclinical studies have shown that lithium alters sodium transport in nerve and muscle cells and effects a shift toward intraneuronal metabolism of catecholamines. Lithium carbonate is indicated in the treatment of manic episodes of manic-depressive illness. Maintenance therapy prevents or diminishes the intensity of subsequent episodes in those manic-depressive patients with a history of mania. lithium carbonate may produce a normalization of symptomatology.


Lithium is used for medical purpose as capsules and tablets form

eg are

Eskalith Capsules

Eskalith Controlled Release Tablets

Lithobid Tablets: