Insulin is a protein hormone created by pancreatic cells in a series of four steps. Arrange the following steps in order by a 1,2,3, or 4 in your...
answers for (a) through (d).
a) _____ Insulin is transported through the cell by the endoplasmic reticulum.
b)_____Insulin is exported into the extracellular fluid by exocytosis.
c)_____The ribosomes manufacture insulin.
d)_____ The golgi apparatus encloses insulin in a secretory vesicle.
Insulin is a peptide hormone (also sometimes called a protein hormone) and it is produced in the pancreas exactly the same way a polypeptide (or protein) is produced in any cell. The first step of polypeptide production is transcription of DNA by messenger RNA (mRNA) in the nucleus. The mRNA is then translated in the ribosomes into an amino acid. Those amino acids are then linked together with peptide bonds to create a polypeptide.
After the protein is produced by the ribosome, they travel through the endoplasmic reticulum to the Golgi apparatus. The Golgi then packages the protein into a vesicle and it is transported throughout the cell. If it is an excretory protein, like insulin, it leaves the cell through exocytosis and travels throughout the body.
__b___ Insulin is transported through the cell by the endoplasmic reticulum.
__d___Insulin is exported into the extracellular fluid by exocytosis.
__a___The ribosomes manufacture insulin.
__c___ The golgi apparatus encloses insulin in a secretory vesicle.