In act 3, scene 3, Romeo discovers that Prince Escalus has banished him from Verona instead of punishing him by death. Romeo responds to this news by acting hysterically and cursing his own name and situation. Friar Lawrence responds by severely chastising Romeo for his overreaction—before the Nurse enters the scene to describe Juliet's broken heart.
In lines 107–108, Romeo curses his last name and threatens to commit suicide by grabbing a dagger. Friar Lawrence is speaking directly to Romeo in lines 109–145, as he instructs Romeo to control his emotions and calm down. Friar Lawrence proceeds to question Romeo's manhood and chastises him for overreacting (and accuses him of acting like a sensitive woman). The Friar goes on to elaborate on all the bad things associated with committing suicide and challenges Romeo to be grateful that he and Juliet are both alive.
Overall, Friar Lawrence is speaking directly to Romeo in act 3, scene 3 (lines 109-145), where he criticizes Romeo for behaving like an irrational, sensitive woman before encouraging him to remain optimistic about his current situation.