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As the plot of Wit progresses, Vivian Bearing becomes increasingly aware that, in regard to the experimental and desperate form of chemotherapy that she is receiving, the doctors are far more concerned with Vivian's value as a test subject than as a patient whose life they may save. She finds this humorously ironic in that, over the course of her life, she has often held the same mindset.

However, Vivian realizes that for all her wit and intellect, none of it has prepared her for the isolation and pain she now faces. In the climax of the play, her old teacher visits Vivian in her dying hours. She offers to read her a sonnet of John Donne, whom Vivian...

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