How exactly are you supposed to comment on the quote? By what it means? The language used here can be taken as a sign of things to come (Elizabeth's eventual death due to Victor's creature) or Victor obsessing with death and the passing of his mother. The entire dream could be seen as Victor having a vision of the future and the horror that his Creature unleashes. There is also a possible Freudian interpretation about Elizabeth becoming Victor's mother. I am not entirely sure what your assignment is, however, so I am not sure what kind of comments you are looking for.